
Daimon Michiko is a 37-year-old freelance surgeon who is part of a questionable “doctor placement service” that has her wander from hospital to hospital. The harsh environment at the hospitals led many doctors to retire from their positions, forcing hospitals to make use of said program to fill the empty spots at least temporary. However, Michiko doesn’t look like a doctor at all with her flashy clothes and eccentric attitude. In the first episode she raises objections to a certain operation which is planned to be done by the head of a hospital who hasn’t performed an operation for a very long time. This causes Michiko to incur odium at the hospital, however, everyone becomes frozen when Michiko points out the outdated skills of the director. She also holds a scrupulous compliance when it comes to her working hours, never does any unnecessary chores that don’t require a medical license, and couldn’t care less about the power struggles within the hospitals. Nobody knows how she acquired such a top-level skill that allows her to claim exorbitant sums as reward, but her private life is an even greater mystery to everyone around her. Tanaka plays a rookie surgeon, Uchida an anesthetist, Kishibe the head of the placement service, and Ito the head of the surgical department of this institution.

Takeshi Hongo is a promising young man with a passion for motorcycle racing. However, his dreams are suddenly ruined when he gets kidnapped by Shocker, the evil secret organization planning to dominate the world. After being remodeled into a cyborg, Takeshi escapes and swears to protect the world from the inhuman monsters.

Detective Ukyo Sugishita confronts crime on the basis of his own convictions. He has a partner that works for him in the Special Task Unit. For the first 7 seasons, Ukyo’s first partner is Kaoru Kameyama. He is a good-natured, hot-tempered, straightforward and somewhat scattered detective. Beginning in Season 8, Takeru Kanbe replaces Kameyama. Contrary to his predecessor, Takeru is a lanky, cool, conceited and confident detective. From Season 11 to Season 13, Ukyo’s partner is a young detective Toru Kai. Toru is a son of Deputy Director-General of The National Police Agency. But he became a detective by his own effort. And starting with Season 14, Ukyo’s current partner is Wataru Kaburagi, an elite bureaucrat who came to the Metropolitan Police Department on temporary assignment. As the first partner without any career of a police officer, he will face challenging cases together with Ukyo.

Centered around typical Japanese food, a solitary salesman travelling through the country for business purposes, eats at its various establishments and experiences the various delicacies of Japanese cuisine.

Satoshi Itomura is an assistant police investigator who belongs to the Metropolitan Police Department’s Scientific Investigation Team. Reenactments, fingerprint and voice data collections, profiling... His team collects scientific evidence and pieces together fragments of information in order to help build evidences. However, Itomura often does not care about the scientific approach and instead pays a great deal of attention to the things that the victims always carried with them or treasured. And he focuses on these things because they usually carry the victim’s dying wishes, understanding that last message not only helps solve the cases but also brings closure to the depressed family of victims.

Izumi Sakuragi is a new police sergeant with the Special Investigations Office, which was set up within the Metropolitan Police in November last year. The new investigation team uses DNA analysis and the latest in forensics science to investigate cold cases as well as cases suspected to involve missing persons.

65 million years ago, the knights of the Ryusoul Tribe were selected to participate in a war campaign against the dictating Druidon Tribe who sought to rule Earth. But the Druidon's war campaign was halted by the meteor that brought the age of the dinosaurs to an end, forcing them to flee into space. Meanwhile, the Kishiryu were placed in a deep sleep as a failsafe should the Druidon return. The chosen knights choose to live in peace while passing their mantle down across generations. In the present day, the Druidon return to reclaim Earth as the current generation of knights, the Ryusoulgers, battle them with the support of Ui Tatsui and her father Naohisa Tatsui.

Yū Amagi is a slightly eccentric detective who has been assigned to the Twelfth Section of the Tokyo Metropolitan Police Department's First Investigative Division from the Lost and Found Centre. The Twelfth Section is called the "graveyard of detectives" and ridiculed as the "banishment room where hardened detectives who cannot be fired are sent." Its assembled detectives Kōsuke Samura, Takumi Yamashita, Keita Nagasawa, Tamaki Mizuta, and Masatoshi Katagiri are elite and yet oddballs. Amagi appears fixated with time which seems to have no relation with a case. Raising questions about the timelines of the perpetrator and victim derived from the estimated time of death, time of crime, time of alibi, and time limit, he searches for the meaning of "blank time" which arises from this. He obsesses over the weight of every minute and second of time because of some incident.

Yū Amagi is a slightly eccentric detective who has been assigned to the Twelfth Section of the Tokyo Metropolitan Police Department's First Investigative Division from the Lost and Found Centre. The Twelfth Section is called the "graveyard of detectives" and ridiculed as the "banishment room where hardened detectives who cannot be fired are sent." Its assembled detectives Kōsuke Samura, Takumi Yamashita, Keita Nagasawa, Tamaki Mizuta, and Masatoshi Katagiri are elite and yet oddballs. Amagi appears fixated with time which seems to have no relation with a case. Raising questions about the timelines of the perpetrator and victim derived from the estimated time of death, time of crime, time of alibi, and time limit, he searches for the meaning of "blank time" which arises from this. He obsesses over the weight of every minute and second of time because of some incident.

Shūichirō Kiriyama works at the Limitation Task Force, the place where the cases which have reached the statute of limitations are destroyed. Getting bored of his job, he decides to find a hobby, because it seems important to him to have a hobby. So he decides to puzzle out the unsolved cases on his free time, helped by his coworker Mikazuki, who seems to have a crush on him.

Ichiro Onizuka is a skilled detective who is confined to a wheelchair after being injured in an incident that occurred right before his retirement. Armed with a detailed "city of memory" in his mind, he solves modern-day cases alongside Saki Toyama and Keitaro Jin, while recalling the cases of the past.

Akira Shimazaki lives with his middle school student son. He used to work as a bodyguard, but, due to an incident, he now works as a security guard at a construction site. The private security company where he works establishes a new bodyguard division. Hiding his past as a bodyguard, Akira Shimazaki begins work as a novice bodyguard.

Aoi Midori is a pharmacist and in the 8-year span of her career, she has worked according to her strong belief that "One must know the patient well in order to prescribe the correct medication as medicine is the bond that connects the patient's today to his/her daily life henceforth". Due to that, Aoi usually takes a long time in her consultations with the patients, and this causes her to be complained by her colleagues for being too inefficient in her work. Aoi shrugs off the complaints as her goal is to help the patients regain the daily life that they once took for granted.

Tsukiko Otonashi is a fashionista who is too beautiful to be a detective. She is also intrigued by urban legends so much so that she believes all crimes are somehow linked to these legends. She even conducts her investigations in such a way as to prove them to be true. Tsukiko also likes to make use of whatever she can. She especially likes to enlist the help of crime lab officer Hitoro Katsuura, who happens to have a crush on her. Many other unique characters will make appearances as she investigates the crimes related to urban legends, using odd and exquisite techniques.

The city is filled with countless urban legends. Strange incidents that occur in the midst of these legends lead people into a labyrinth... It is the five young detective hatchlings who take on these difficult cases. Overflowing with intellectual curiosity, they make the most of their abilities. They are full of intellectual curiosity and show their abilities to the fullest as they run through the city and get to the bottom of the mystery. And what lurks behind the scenes is a professional criminal planner... Through fierce battles with the enemy and encounters with various people, they are sometimes hurt, but they gradually grow up. This is a pop youth mystery that depicts the friendship and adventures of a group of talented detectives.