
Richard Kimble is falsely convicted of his wife's murder and given the death penalty. En route to death row, Kimble's train derails and crashes, allowing him to escape and begin a cross-country search for the real killer, a "one-armed man". At the same time, Dr. Kimble is hounded by the authorities, most notably dogged by Police Lieutenant Philip Gerard.

A band of Mexicans find their U. S. land claims denied and all the records destroyed in a courthouse fire. Their leader, Louis Chama, encourages them to use force to regain their land. A wealthy landowner wanting the same decides to hire a gang of killers with Joe Kidd to track Chama.

After a film production wraps in Peru, an American wrangler decides to stay behind, witnessing how filmmaking affects the locals.

